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In 2020, ATNAHS added Rocaltrol (calcitriol) to their portfolio of heritage brands

In 2020 ATNAHS acquired the global commercial rights (excluding China and Japan) for Rocaltrol (calcitriol) from Roche.

Rocaltrol (calcitriol) is the active form of Vitamin D, primarily used in the treatment of post-menopausal osteoporosis and renal osteodystrophy.1

History and development of Rocaltrol (calcitriol)

Image of Dr Michael F. Holick

Rocaltrol was first approved by the FDA in 1998,2 although it was Dr Michael F. Holick, currently Director of the Bone Health Clinic, Boston University, USA, who made the original discovery of the active form of vitamin D in 1971.3

Dr Holick’s scientific work increased awareness among the medical community of the wide-ranging effects of vitamin D deficiency and of the beneficial effects of Vitamin D to the general public.3

A molecule whose revenues continue to grow

Calcitriol market expected to generate revenues of $470 million by 20244

According to a recent report, the global market for calcitriol was valued at $350 million in 2017 and is expected to continue growing.4

2 million prescriptions in 20185

In 2018, there were almost two million prescriptions written for calcitriol.5


All of the information presented above is factual historical information that is available in the public domain and is included in good faith. It is not the intention to make any new or fresh claims nor to be promotional for the product in question.


  1. Rocaltrol 0.5mg capsules, Summary of Product Characteristics.
  2. FDA. U.S. Food and Drug Administration. 1998. Available from https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=reportsSearch.process&rptName=2&reportSelectMonth=11&reportSelectYear=1998&nav [Last accessed January 2021].
  3. Michael Holick, PhD, MD: Vitamin D Pioneer. Alternative Therapies, May/Jun 2008, Vol. 14, No. 3. Available from http://www.alternative-therapies.com/at/web_pdfs/0508_interview.pdf [Last accessed January 2021].
  4. Zion Market Research. Available from https://www.globenewswire.com/news-release/2018/12/12/1665749/0/en/Global-Calcitriol-Market- Expected-to-Reach-USD-470-Million-By-2024-Zion-Market-Research.html [Last accessed January 2021].
  5. The Top 300 of 2021. ClinCalc.com Available from https://clincalc.com/DrugStats/Top300Drugs.aspx [Last accessed January 2021].

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